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Cycloaddition Reactions of Some Tricyclic Imides

[ Vol. 10 , Issue. 4 ]

Author(s):

Irem Kulu, Melek Gul, Omer Tahir Gunkara and Nuket Ocal   Pages 409 - 418 ( 10 )

Abstract:


Our research group has published numerous papers over the last three years on the reaction of nitrile oxides and azomethine ylide with unsaturated tricyclic N-substituted dicarboximides selected according to the importance of possible biological activities. These reactions cover full range of mechanistic pathways and timings of bond-forming processes to give five-membered ring closure by 1,3-dipolar cycloaddition.

Keywords:

Azomethine ylide, biological active molecules, 1, 3-dipolar cycloaddition, hydrazones, isoxazolines, nitrile oxides, tricyclic imides.

Affiliation:

Yildiz Technical University, Faculty of Science and Arts, Davutpasa Campus, 34220 Istanbul, Turkey.



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