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Review of Characteristics, Pharmacology, Determination and Pharmacokinetics of Rhaponticin

[ Vol. 14 , Issue. 1 ]

Author(s):

Yang Sun, Xuhua Liang, Hua Cheng, Wanqiang Wang, Xiangsheng Jiang, Ping He, Yingyong Zhao and Junjun Wu   Pages 24 - 34 ( 11 )

Abstract:


Rhaponticin (RHA) is a stilbene glucoside compound that can be found in medicinal plant of Rheum L. RHA has been reported to possess several biological effects including antitumor, antithrombotic, antioxidant, vasorelaxant, defense for gastritis activities. It also shows beneficial activities on diabetic mice. According to reported literatures, an overview of spectroscopy characteristics, pharmacological activity, content determination and pharmacokinetics, etc. for RHA has been presented. Moreover, this work provides a certain reference value for developing the therapeutic drug of RHA.

Keywords:

Rhaponticin, stilbene glucoside, anti-diabetic activity, structural characteristics of RHA, anti-oxidation activity, anti-allergic activity.

Affiliation:

School of chemical engineering and food science, Hubei University of Arts and Science, No. 296 Longzhong Road, Xiangyang, Hubei 441053,, College of Biology Pharmacy and Food Engineering, Shangluo University, Shangluo 726000,, School of Chemical Engineering and Food Science, Hubei University of Arts and Science, No. 296 Longzhong Road, Xiangyang, Hubei 441053,, School of Chemical Engineering and Food Science, Hubei University of Arts and Science, No. 296 Longzhong Road, Xiangyang, Hubei 441053,, School of Chemical Engineering and Food Science, Hubei University of Arts and Science, No. 296 Longzhong Road, Xiangyang, Hubei 441053,, School of Chemical Engineering and Food Science, Hubei University of Arts and Science, No. 296 Longzhong Road, Xiangyang, Hubei 441053,, College of Life Sciences, Northwest University, No.229 Taibai North Road, Xi`an, Shaanxi 710069,, School of chemical engineering and food science, Hubei University of Arts and Science, No. 296 Longzhong Road, Xiangyang, Hubei 441053

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