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Progress of Trifluoroacetoacetate in the Synthesis of Agrochemicals and Medicines with Fluorine

[ Vol. 14 , Issue. 5 ]

Author(s):

Yuechao Wu , Yulin Wang , Mingping He , Xiaohong Tao , Jianguang Li , Danping Shan and Liang Lv   Pages 350 - 356 ( 7 )

Abstract:


Fluorinated medicines have become research emphasis in the fields of pesticides and medicines due to their advanced properties. Trifluoroacetoacetate (TFAAE) is an important intermediate for the synthesis of pesticide, medicine and other fluorine compounds. As a useful building block containing trifluoromethyl, TFAAE is widely used in the synthesis of heterocyclic drugs, insecticides and herbicides. In this paper, the preparation methods of TFAAE and the advanced applications in agrochemicals and medicines with fluorine are introduced in detail

Keywords:

Trifluoroacetoacetate, Ethyl 4, 4, 4-trifluoroacetoacetate, trifluoromethyl, agrochemicals, fluorine heterocyclic compound.

Affiliation:

College of Chemical & Materials Engineering, Quzhou University, Zhejiang 324000, College of Chemical and Materials Engineering, 78 Jiu Hua Bei Da Dao, Quzhou City, Zhejiang Province, 324000, Quzhou University, College of Chemical & Materials Engineering, Quzhou University, Zhejiang 324000, College of Chemical & Materials Engineering, Quzhou University, Zhejiang 324000, College of Chemical & Materials Engineering, Quzhou University, Zhejiang 324000, College of Chemical & Materials Engineering, Quzhou University, Zhejiang 324000, College of Chemical and Materials Engineering, 78 Jiu Hua Bei Da Dao, Quzhou City, Zhejiang Province, 324000, Quzhou University

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