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Organocatalyzed Asymmetric Diels-Alder Reactions in Aqueous or Semi- Aqueous Media

[ Vol. 15 , Issue. 1 ]

Author(s):

Kartick C. Bhowmick, Manisha Bihani and John C.-G. Zhao*   Pages 3 - 19 ( 17 )

Abstract:


Background: The Diels-Alder reaction is one of the most important reactions in organic synthesis.

Objective: Recently there has been considerable interest in conducting this important reaction in aqueous or semi-aqueous media using organocatalysts due to the green nature of the water solvent and organocatalysts as well as the special solvent effects of water on organic reactions.

Conclusion: This review attempts to summarize the most recent developments in organocatalytic asymmetric Diels-Alder reactions using water as a solvent or a co-solvent.

Keywords:

Diels-Alder reaction, organocatalysis, asymmetric, water, renewable solvent, green chemistry, semi-aqueous media.

Affiliation:

Department of Chemistry, University of Texas at San Antonio, One UTSA Circle, San Antonio, Texas 78249-0698, Department of Chemistry, University of Texas at San Antonio, One UTSA Circle, San Antonio, Texas 78249-0698, Department of Chemistry, University of Texas at San Antonio, One UTSA Circle, San Antonio, Texas 78249-0698

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