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Synthesis of Quinoxaline-Based Compounds and Their Antitumor and Antiviral Potentials

[ Vol. 15 , Issue. 3 ]

Author(s):

Jelena Petronijevic*, Nenad Jankovic and Zorica Bugarcic   Pages 220 - 226 ( 7 )

Abstract:


Background: Quinoxaline-based derivatives present a group of very important heterocyclic pharmacophores which occupied the attention of a large number of scientists in the last few decades. Compounds with quinoxaline fragment have significant antitumor and antiviral potential, proved by an in vitro or/and in vivo study, and possess therapeutic potential.

Conclusion: In this review article, we present an overview of the developments in the area of synthesis of compounds that contain quinoxaline scaffold with antitumor or antiviral activities.

Keywords:

o-Phenylenediamine, Diketo acid, quinoxaline, antitumor activity, antiviral activity, benzodiazepene.

Affiliation:

Department of Chemistry, Faculty of Science, University of Kragujevac, Kragujevac, Department of Chemistry, Faculty of Science, University of Kragujevac, Kragujevac, Department of Chemistry, Faculty of Science, University of Kragujevac, Kragujevac

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