Thies Thiemann* Pages 412 - 432 ( 21 )
Wittig- and Horner-Wadsworth-Emmons (HWE) olefination remains a series of powerful reactions in the tool kit of organic synthesis. In the following article, an overview of the scope of Wittig and HWE olefination reactions in water or in multiphasic media under phase transfer conditions is presented. Special emphasis is given to one-pot, multi-component transformations. In the following article, the work on Wittig- and Horner-Wadsworth-Emmons reactions in aqueous media and under LL-PTC conditions is reviewed.
Wittig reaction, Horner-Wadsworth-Emmons reaction, water, green chemistry, one-pot reaction, phase transfer.
Department of Chemistry, College of Science, United Arab Emirates University, Al Ain, PO Box 15551