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The Synthesis and Use of BMS 204352 (MaxiPostTM)

Author(s):

Renato Dalpozzo*   Pages 1 - 7 ( 7 )

Abstract:


MaxiPostTM is an interesting 3-fluorooxindole derivative, discovered in the late nineties of the last century as potassium channel opener. Since then, two different research fields were discovered: the discovery of new synthetic methods, especially asymmetric ones, and the in vitro and in vivo tests for its use as a drug for different diseases. This mini-review aims to summarize the state of art in both fields.

Keywords:

Maxipost, Asymmetric synthesis, drug siscovery, oxindoles

Affiliation:

Department Chimica e Tecnologie Chimiche, University of Calabria, I-87036 Arcavacata di Rende (Cs)



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