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A Mini-Review: Achievements in the Thiolysis of Epoxides

Author(s):

Zhihua Chen, Saeed Mohammadi Nasr, Mosstafa Kazemi* and Masoud Mohammadi   Pages 1 - 11 ( 11 )

Abstract:


The β-hydroxy sulfides are an important class of organosulfur compounds that have a key role in the synthesis of bioactive compounds containing biological and natural products. The thiolysis of epoxides is the most common and best route for the synthesis of β-hydroxy sulfides. During the last decade, the application a diverse range of catalysts and promoter agents in green and organic mediums as well as under solvent-free conditions for the regioselective ring-opening reactions of epoxides with thiols in order to synthesize β-hydroxy sulfides have been studied by various research groups. This review is focused on the recent reported achievements in the field of thiolysis of epoxides within the last 10 years.

Keywords:

β-Hydroxy sulfides, Thiolysis, Epoxides, Biological, Organosulfur compounds.

Affiliation:

Institute of Computing Science and Technology, Guangzhou University, Guangzhou 510006, Chemical Engineering Faculty, Sahand University of Technology, Tabriz, Department of Chemistry, Faculty of Basic Sciences, Ilam University, P.O. Box 69315-516, Ilam, Department of Chemistry, Faculty of Basic Sciences, Ilam University, P.O. Box 69315-516, Ilam



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