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A Mini-Review: Achievements in the Thiolysis of Epoxides

[ Vol. 17 , Issue. 4 ]

Author(s):

Zhihua Chen, Saeed Mohammadi Nasr, Mosstafa Kazemi* and Masoud Mohammadi   Pages 352 - 362 ( 11 )

Abstract:


The β-hydroxy sulfides are an important class of organosulfur compounds that have a key role in the synthesis of bioactive compounds containing biological and natural products. The thiolysis of epoxides is the most common and best route for the synthesis of β-hydroxy sulfides. During the last decade, the applications of a diverse range of catalysts and promoter agents in green and organic mediums as well as under solvent-free conditions for the regioselective ring-opening reactions of epoxides with thiols in order to synthesize β-hydroxy sulfides have been studied by various research groups. This review is focused on the important achievements reported in the literature for the thiolysis of epoxides.

Keywords:

Biological, epoxides, organosulfur compounds, thiolysis, β-hydroxy sulfides, catalysts.

Affiliation:

Institute of Computing Science and Technology, Guangzhou University, Guangzhou 510006, Independent Researcher, Jowlan 65136-8942, Hamedan, Department of Chemistry, Faculty of Science, Ilam University, PO Box, 69315516 Ilam, Department of Chemistry, Faculty of Science, Ilam University, PO Box, 69315516 Ilam

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