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C-Methylation of Organic Substrates: A Comprehensive Overview. Part I. Methane as a Methylating Agent

[ Vol. 17 , Issue. 7 ]

Author(s):

Saad Moulay*   Pages 805 - 813 ( 9 )

Abstract:


A literature survey on C-methylation of organic substrates with methane as a methylating agent is analyzed. Of the substrates that undergo C-methylation are benzene, naphthalenes, toluene, alkanes, alkenes, acetonitrile, and other functionalized organic compounds. None of these methylation reactions occur in the absence of a catalyst. A direct introduction of a methyl group on the carbon sites of a molecule is concomitant with the formation of other products, as a result of either a possible rearrangement or a further reaction with methane. Mechanistically, the C-methylation with methane proceeds oxidatively. The products selectivities depend on several factors, mainly on the acid/ base character of the solid catalyst.

Keywords:

Benzene, catalyst, methane, methylating agent, methylation, toluene.

Affiliation:

Laboratoire de Chimie-Physique Moleculaire et Macromoleculaire, Departement de Genie des Procedes, Faculte de Technologie, Universite Saad Dahlab de Blida, B. P. 270, Route de Soumaa, 09000, Blida

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