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Formation of Carbon-Oxygen Bond Mediated by Hypervalent Iodine Reagents Under Metal-Free Conditions

[ Vol. 18 , Issue. 5 ]

Author(s):

Ayesha Jalil, Yaxin O. Yang, Zhendong Chen, Rongxuan Jia, Tianhao Bi, Xuemin Li and Yunfei Du*   Pages 540 - 605 ( 66 )

Abstract:


Hypervalent iodine reagents are a class of non-metallic oxidants that have been widely used in the construction of several sorts of bond formations. This surging interest in hypervalent iodine reagents is essentially due to their very useful oxidizing properties, combined with their benign environmental character and commercial availability from the past few decades ago. Furthermore, these hypervalent iodine reagents have been used in the construction of many significant building blocks and privileged scaffolds of bioactive natural products. The purpose of writing this review article is to explore all the transformations in which carbon-oxygen bond formation occurs by using hypervalent iodine reagents under metal-free conditions.

Keywords:

Dess-Martin periodinane, C-O bond formation, dichloroiodobenzene, hypervalent iodine reagent, metal-free conditions, oxidation.

Affiliation:

Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072

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