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A Short Review on the Synthesis of 1,2,4-Triazine Derivatives as Bioactive Compounds

[ Vol. 18 , Issue. 8 ]

Author(s):

Heba E. Hashem*   Pages 1127 - 1133 ( 7 )

Abstract:


Triazines and their oxo derivatives are a representative class of heterocyclic compounds which have attracted great attention in organic synthesis and medicinal chemistry as they have been associated with a broad range of pharmacological activities. 1,2,4-Triazines and their oxo derivatives exhibit a broad range of biological activities, including antimicrobial, antifungal, anticancer, antiinflammatory, besides having importance in the dyes and pesticides field. This review presents the different methods of the synthesis of triazine/one derivatives. Also, this literature surveys the different effects of these compounds in pharmaceuticals.

Keywords:

1, 2, 4-Triazine, fused triazine, heterocycles, biological activity, synthesis, oxo derivatives.

Affiliation:

Department of Chemistry, Faculty of Women, Ain Shams University, Heliopolis, Cairo 11757

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